1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride

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What is the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride ?

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride is , while it's Molecular Formula is C12H15 N . Cl H. MPTP is a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPTP is metabolized by monoamine oxidase B to produce MPDP+ and MPP+, with MP+ being the active toxic agent. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative stress. The key features of different neurotoxic models of Parkinson’s disease, including the MPTP model, have been detailed.[Cayman Chemical]

What is the CAS number for 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride ?

The CAS number of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride is 23007-85-4.

More information of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride 23007-85-4 are:

What is 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (23007-85-4) used for?

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride, commonly known as MPTP, is a synthetic chemical compound with a white solid appearance. It is classified as a dopaminergic neurotoxin that has been found to induce severe and irreversible Parkinsonian symptoms in both humans and monkeys.

InChI:InChI=1/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H

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