What is the CAS number for Molidustat(BAY 85-3934)?

The CAS number of Molidustat(BAY 85-3934) is 1154028-82-6.

What is Molidustat(BAY 85-3934) (1154028-82-6) used for?

Hypoxia-inducible factor (HIF) is the major transcription factor involved in erythropoietin gene expression. Because oxygen-dependent degradation of the a subunit of HIF suppresses erythropoietin expression, stimulation of erythropoiesis by agents that prevent degradation of HIF has been one strategy for managing anemia. BAY 85-3934 stabilizes HIF from degradation in the proteasome by inhibiting HIF-1a prolyl hydroxylase (IC50 = 0.49 µM). Inhibition of HIF prolyl hydroxylase by BAY 85-3934 has been shown to increase endogenous production of erythropoietin. Molidustat(BAY 85-3934) has been investigated in clinical trial for treatment of patients with anemia associated with chronic kidney disease and/or end-stage renal disease.

What is the CAS number for Molidustat(BAY 85-3934)?

The CAS number of Molidustat(BAY 85-3934) is 1154028-82-6.

What is Molidustat(BAY 85-3934) (1154028-82-6) used for?

Hypoxia-inducible factor (HIF) is the major transcription factor involved in erythropoietin gene expression. Because oxygen-dependent degradation of the α subunit of HIF suppresses erythropoietin expression, stimulation of erythropoiesis by agents that prevent degradation of HIF has been one strategy for managing anemia. BAY 85-3934 stabilizes HIF from degradation in the proteasome by inhibiting HIF-1α prolyl hydroxylase (IC50 = 0.49 μM). Inhibition of HIF prolyl hydroxylase by BAY 85-3934 has been shown to increase endogenous production of erythropoietin. Molidustat(BAY 85-3934) has been investigated in clinical trial for treatment of patients with anemia associated with chronic kidney disease and/or end-stage renal disease.

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What is the Molidustat(BAY 85-3934) ?

Molidustat(BAY 85-3934) is , while it's Molecular Formula is C13H14N8O2.

How to get the best price on Molidustat(BAY 85-3934)?

Qingdao Spring Chemical Co.,Ltd. is a quality supplier and manufacturer of Molidustat(BAY 85-3934) . You can buy high quality, low price Molidustat(BAY 85-3934) 1154028-82-6 here. Contact us.

Mucopolysaccharides, glycosaminoglycans, chondroitin sulfate-dermatan sulfate-contg., skin

4-Methoxyindole

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione

N2-[(1R,2S)-2,6-dimethylindan-1-yl]-6-(1-fluoroethyl)-1,3,5-triazine-2,4-diamine

1,5-DIPHENYLCARBAZIDE

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Molidustat(BAY 85-3934)

What is the Molidustat(BAY 85-3934) ?

How to get the best price on Molidustat(BAY 85-3934)?

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