Geneticin

Factory supply Geneticin 108321-42-2 with sufficient production capacity We provide high quality Geneticin (CAS 108321-42-2), at a very affordable prices to our customers.

1.What is the Geneticin ?

Geneticin (also known as G418, G418 sulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research to select genetically engineered cells. Resistance to Geneticin is conferred by the neo gene from Tn5 encoding an aminoglycoside 3'-phosphotransferase, APH 3'II.

Geneticin is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL. It is also used to membrane-permeant allosteric effector of hemoglobin therapeutic in cardiovascular diseases and cancer.

2.What is the CAS number for Geneticin ?

The CAS number of Geneticin is 108321-42-2.

More information of Geneticin 108321-42-2 are:

3.What is the molecular formula of Geneticin ?

The chemical formula of?Geneticin is C20H40N4O10^. 2(H2SO4) which containing 20 Carbon atoms,42 Hydrogen atoms,4 Nitrogen atoms,2 Oxygen atoms and 1 Sulfur atoms,and the molecular weight, and the molecular weight of Geneticin is 692.70

4.What is Geneticin(108321-42-2)used for?

Geneticin (also known as G418, G418 sulfate) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research to select genetically engineered cells. Resistance to Geneticin is conferred by the neo gene from Tn5 encoding an aminoglycoside 3'-phosphotransferase, APH 3'II.

InChI:InChI=1/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9-,10-,11+,12-,13-,14-,15+,16?,17-,18-,19?,20+;;/m1../s1

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5.Factory supply Geneticin 108321-42-2 with sufficient production capacity

Qingdao Spring Chemical Co.,Ltd. is a quality supplier of Geneticin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Geneticin 108321-42-2.