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Antazoline hydrochloride

  • CAS：2508-72-7
  • purity：99%
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Buy Good Quality Antazoline hydrochloride 2508-72-7 with a minimum purity of 99%

  • Molecular Formula: C17H19N3 .HCl
  • Molecular Weight: 301.819
  • Appearance/Colour: White or almost white crystalline powder 
  • Vapor Pressure: 3.31E-09mmHg at 25°C 
  • Melting Point: 238 °C 
  • Boiling Point: 475.5 °C at 760 mmHg 
  • Flash Point: 241.4 °C 
  • PSA： 27.63000 
  • LogP: 3.26130 

Antazoline hydrochloride(Cas 2508-72-7) Usage

Manufacturing Process

15.4 parts of 2-chloromethylimidazoline hydrochloride, 45.8 parts of Nbenzylaniline and 150 parts of alcohol are heated in an oil bath at 100° to 110°C. After distilling off the alcohol, the reaction mass is maintained at this temperature for a further 3 hours and then triturated with water and 10 parts of sodium bicarbonate. The unconsumed benzylaniline is extracted with ether and the aqueous solution neutralized with dilute hydrochloric acid. By evaporating this solution and extracting the residue with alcohol there is obtained 2-(N-phenyl-N-benzylaminomethyl)imidazoline hydrochloride in the form of colorless crystals of melting point 227° to 229°C.

Therapeutic Function

Antihistaminic

Biological Activity

Imidazoline binding site ligand; a potent inducer of insulin secretion in rat pancreas. Also an antihistamine.

InChI:InChI=1/C17H19N3/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16/h1-10H,11-14H2,(H,18,19)/p+1

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