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Omecamtiv mecarbil

  • CAS：873697-71-3
  • purity：99%
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Quality products?make an important contribution to long-term revenue and profitability. Factory supply Omecamtiv mecarbil 873697-71-3 with sufficient stock and high standard

1.What is the Omecamtiv mecarbil ?

CK 1827452 is a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction.

5-isocyanato-2-methylpyridine
732245-99-7

5-isocyanato-2-methylpyridine

methyl 4-(3-amino-2-fluorobenzyl)piperazine-1-carboxylate
873697-70-2

methyl 4-(3-amino-2-fluorobenzyl)piperazine-1-carboxylate

methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl]piperazine-1-carboxylate
873697-71-3

methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl]piperazine-1-carboxylate

Conditions
Conditions Yield
In acetone; at 20 ℃; Heating/reflux;
86%
In acetone; at 20 ℃; Heating / reflux;
86%
In acetone; at 20 ℃; for 6.65h; Heating / reflux;
86%
In acetone; at 20 ℃; Heating / reflux;
73%
In acetone; for 6.5h; Heating / reflux;
73%
methyl 4-(3-amino-2-fluorobenzyl)piperazine-1-carboxylate
873697-70-2

methyl 4-(3-amino-2-fluorobenzyl)piperazine-1-carboxylate

C<sub>13</sub>H<sub>12</sub>N<sub>2</sub>O<sub>2</sub>*(x)ClH

C13 H12 N2 O2 *(x)ClH

methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl]piperazine-1-carboxylate
873697-71-3

methyl 4-[(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}phenyl)methyl]piperazine-1-carboxylate

Conditions
Conditions Yield
With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; acetonitrile;
80%

2.What is the CAS number for Omecamtiv mecarbil ?

The CAS number of Omecamtiv mecarbil is 873697-71-3.

More information of Omecamtiv mecarbil 873697-71-3 are:

CAS?Number

873697-71-3

Density

1.344 g/cm3

Melting Point

180℃

Boiling Point

456.78 °C at 760 mmHg

Flash Point

230.052 °C

PSA

90.29000

LogP

3.01950

3.What are another words for Omecamtiv mecarbil ?

Synonyms?for?Omecamtiv mecarbil 873697-71-3:CK 1827452;UNII-2M19539ERK;Methyl 4-((2-fluoro-3-(((6-methylpyridin-3-yl)carbamoyl)amino)phenyl)methyl) piperazine-1-carboxylate;

4.What is the molecular formula of Omecamtiv mecarbil?

The chemical formula of ?Omecamtiv mecarbil is?C20H24FN5O3 which containing 20 Carbon atoms,24 Hydrogen atoms,1 Fluorine atoms,5 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of??Omecamtiv mecarbil?is 401.441.

5.What is Omecamtiv mecarbil (873697-71-3) used for?

Omecamtiv mecarbil (CK-1827452) is a specific cardiac myosin activator and a clinical drug for left ventricular systolic heart failure. Phase 2.

Relevant articles related to Omecamtiv mecarbil:

Article

Source

SYNTHESIS OF OMECAMTIV MECARBIL

-

Paragraph 0049, (2019/01/17)

Palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate: A practical synthesis of unsymmetrical ureas

Vinogradova, Ekaterina V.,Fors, Brett P.,Buchwald, Stephen L.

, p. 11132 - 11135 (2012/08/28)

6.Buy Omecamtiv mecarbil with the best price .

Qingdao Spring Chemical Co.,Ltd. is a quality supplier of Omecamtiv mecarbil. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Omecamtiv mecarbil 873697-71-3.

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